Alpha-1-Antitrypsin (Dako Omnis)

Alpha-1-antitrypsin (A1AT) is a 51 kDa glycoprotein mainly synthesized in the liver. It is an acute phase protein and functions as a major inhibitor of serine proteases. A1AT is present in normal liver cells, histiocytes and monocytes, and in a large variety of tumors of both epithelial and mesenchymal differentiation.