Carcinoembryonic Antigen (Dako Omnis)

Monoclonal antibodies to CEA have been classified into five essentially non-interacting epitope groups, designated Gold 1 to 5. Dako Anti-CEA, clone II-7, belongs to epitope group Gold 1 and shows a high degree of CEA specificity (1). The antibody is a useful aid for classification of adenocarcinomas, notably in the gastrointestinal tract, including colonic and pancreatic carcinomas. Results also aid in the classification of secretory meningiomas (2) and medullary carcinoma of the thyroid (3).