CD2

Anti-human CD2 antibodies for use in flow cytometry. These single-color reagents are of value to the study of normal and neoplastic thymocytes, T lymphocytes and natural killer cells, being considered a pan-T-cell marker.CD2 primarily binds CD58 on antigen-presenting cells and induces costimulatory signals in T cells. CD2 is one of the earliest T-cell lineage-restricted antigens to appear during T-cell differentiation, and it is expressed on most thymocytes, peripheral T cells and NK cells. Aberrant CD2 expression has been found in some acute myeloid leukaemias almost exclusively restricted to the M3 and M4Eo variants.Further information and references to relevant literature are available in the product’s Instructions For Use.