The Agilent Femto Pulse System offers an excellent solution for analyzing high molecular weight DNA samples with high accuracy. Utilizing pulsed-field electrophoresis technology, this system delivers precise quantification and qualification of DNA samples up to 165 kb, crucial for evaluating the quality of long-read sequencing libraries and predicting the average read length in long-read NGS.In comparison to other non-denaturing gel-based analytical instruments, the Femto Pulse System stands out by achieving significantly higher sensitivity for nucleic acid smears and fragments. This capability enables the detection of low-abundance samples, making it an ideal instrument for highly sensitive analysis of RNA or cfDNA samples.