Granzyme B (Concentrate)

Recognizes granzyme B, a 29 kDa serine protease with chymotrypsin-like substrate specificity. Cytotoxic T lymphocytes (CTL) and natural killer (NK) cells are the major acteurs in the elimination of neoplastic and virally infected cells. The antibody is a useful aid for classification of T/NK-cell lymphomas with cytotoxic phenotypes.