The GTxResolve Premier SEC 1000 Å, 3 μm, 4.6 x 150 mm Column is manufactured with low adsorption MaxPeak HPS hardware and novel bridged ethylene HO-PEO particles to support high recovery analyses of 200 to 800Å diameter GTx drugs, such as mRNA, LNPs, and viral vectors. This column technology provides long column lifetimes, low secondary interactions, and improved MALS sensitivity. Facilitate the development of platform multiattribute SEC assays for mRNA integrity and LNP formulations analyses as well as improved detection of ejected transgenes and aggregates related to viral vectors.
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Chemistry
SEC
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Separation Mode
SEC
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Particle Substrate
Silica
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pH Range Min
2.5 pH
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pH Range Max
8 pH
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Temperature Limits
60 C
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Maximum Pressure
2300 psi (160 Bar)
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Endcapped
No
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Bonding Technology
SEC
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Silanol Activity
Low
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Particle Shape
Spherical
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Particle Size
3 µm
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Endfitting Type
Parker-style
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Pore Size
1000 Å
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QC Tested
Nucleic Acid, Protein
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Format
Premier FIT Cartridge
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Surface Area
24
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System
UHPLC, UPLC, HPLC
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Particle Technology
Silica
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Technique
SEC
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USP Classification
L33
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Inner Diameter
4.6 mm
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Length
150 mm
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Carbon Load
1 %
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UNSPSC
41115709
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Application
Gene Therapeutics
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Brand
GTxResolve
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Product Type
Columns
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Units per Package
1 pk