Kinetex 2.6 µm PS C18 100 Å, LC Column 150 x 4.6 mm, Ea
Бренд: Phenomenex
Selectivity for Polar Basic Compounds
A multi-interaction, 100 % aqueous C18 column that provides great peak shape for basic compounds under low pH conditions and without sacrificing hydrophobic selectivity.
Unique Polar Basic Selectivity
The Kinetex PS C18 combines a 100 % aqueous stability C18 stationary phase, with a unique positive surface charge, and the core-shell advantage to deliver both excellent performance and reversed phase selectivity. Upgrade your traditional fully porous particle to a Kinetex PS C18 Core-Shell particle to take full polar advantage of your systems analytical capabilities. Under identical running conditions and analytes, the Kinetex PS C18 column below demonstrates unique polar selectivity with peaks associated with nortriptyline and 3-methyl 4-nitrobenzoic acid.
Basic Selectivity Comparison
| Column: Kinetex 2.6 µm PS C18 Kinetex 2.6 µm XB-C18 | |
| Dimension: 50 x 4.6 mm | |
| Mobile Phase: A: Water with 0.1 % Formic Acid B: Acetonitrile with 0.1 % Formic Acid | |
| Gradient: Time (min) 0 5 6 6.1 9 | % B 5 95 95 5 5 |
| Flow Rate: 1.85 mL/min | |
| Temperature: 30 °C | |
| Injection Volume: 1 µL | |
| Detection: UV @ 254 nm | |
| Samples: 1. Uracil 2. Pindolol 3. Chlorpheniramine 4. Nortriptyline 5. 3-methyl-4-nitrobenzoic Acid 6. 2-hydroxy-5-methylbenzaldehyde 7. Hexanophenone | |
Take Advantage of the Right Phase for the Application
While traditional alkyl C18 phases are prone to peak tailing for basic compounds due to of secondary interactions occurring at the silica surface, the surface of the Kinetex PS C18 was designed with positive charges that serve to repel basic species and deliver consistently sharper peak shape for basic compounds.
Core-Shell Comparison
| Column: Kinetex 2.6 µm PS C18 Core-Shell 2.6 µm C18 | |
| Dimension: 50 x 4.6 mm | |
| Mobile Phase: A: Water with 0.1 % Formic Acid B: Acetonitrile with 0.1 % Formic Acid | |
| Gradient: Time (min) 0 2 3 3.1 5 | % B 25 35 95 25 25 |
| Flow Rate: 1.85 mL/min | |
| Temperature: Ambient | |
| Injection Volume: 5 µL | |
| Detection: UV @ 254 nm | |
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