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A C18 With a Positive Twist
Luna Omega PS C18 has been fine tuned and manufactured by Phenomenex to provide a mixed selectivity that is highly useful for method development involving either combinations of polar and nonpolar compounds, or just one single compound class with small changes in functional groups.
Enhanced Selectivity and Polar Retention
MMA and Succinic Acid
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Columns:
Luna Omega 1.6 μm PS C18 ACE Excel 2 μm C18-AR
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Dimension:
50 x 2.1 mm
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Mobile Phase:
A: Water with 0.1 % Formic Acid B: Acetonitrile with 0.1 % Formic Acid
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Gradient:
Time (min)
0 5 5.1 7
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% B
0 50 0 0
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Flow Rate:
0.5 mL/min
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Temperature:
22 °C
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Detection:
MS/MS (SCIEX® API 4000™)
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Samples:
1. Succinic acid 2. MMA
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Think Outside the Traditional C18 Selectivity
Acids/Bases/Neutrals
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Columns:
Luna Omega 1.6 μm PS C18 ACQUITY BEH 1.7 μm C18
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Dimension:
50 x 2.1 mm
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Mobile Phase:
A: Water with 0.1 % Formic Acid B: Acetonitrile with 0.1 % Formic Acid
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Gradient:
Time (min)
0 5 5.01 8
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% B
5 95 5 5
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Flow Rate:
0.4 mL/min
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Temperature:
22 °C
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Detection:
UV @ 254 nm
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Samples:
1. Uracil 2. Pindolol 3. Chlorpheniramine 4. Nortriptyline 5. 3-Methyl-4-nitrobenzoic acid 6. 5-Methyl salicylaldehyde 7. Hexanophenone
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Better Peak Shape for Bases
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