OneSeq CNV Backbone + SureSelect Custom Panels

Comprehensive, all-in-one detection of genome-wide CNVs, copy-neutral LOH (cnLOH), SNPs, and indels in one target enrichment capture.Study both CNVs and mutations for your constitutional studies using one assay. OneSeq’s CNV backbone targets a functional copy number resolution of 300 Kb in the genome-wide backbone. OneSeq CNV backbone targets an even higher resolution of 25−50 Kb targeted in disease associated regions as defined by ClinGen. The targeting of genomic regions with high minor allele frequency SNPs allows for detection of copy neutral LOH at 5 Mb resolution.