Wilms’ Tumor 1 Protein (Autostainer Link 48)

WT1 is a gene involved in the induction of Wilms’ tumor, a pediatric renal malignancy. Wilms’ tumor 1 protein regulates transcription of other genes and can function both as a transcriptional activator and repressor. The antibody reacts with all isoforms of the full-length WT1 and also identifies WT1 lacking exon 2-encoded amino acids. Results aid in the classification of Wilms’ tumors, malignant mesotheliomas and acute leukemias.