Waters Oligonucleotide Separation Technology columns are based on the second generation of hybrid-silica BEH Technology particles functionalized with C18. The separation of detritylated synthetic oligonucleotide samples is based on the well-established method of ion-pair, reversed-phase chromatography. The availability of 1.7µm UPLC technology or 2.5µm HPLC particles in various column dimensions provides flexibility to meet various laboratory-scale isolation or analysis needs and delivers exceptional sample resolution and superior column life. In addition, Waters manufacturing and quality control testing procedures help ensure consistent batch-to-batch and column-to-column performance regardless of application demands.
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Chemistry
C18
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Separation Mode
Reversed Phase
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Particle Substrate
Hybrid
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pH Range Min
1 pH
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pH Range Max
12 pH
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Endcapped
Yes
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Silanol Activity
Low
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Particle Shape
Spherical
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Particle Size
2.5 µm
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Endfitting Type
Waters
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Pore Size
130 Å
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QC Tested
Oligonucleotide
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Format
OBD Prep Column
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Surface Area
185
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System
HPLC
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Particle Technology
BEH
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USP Classification
L1
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Inner Diameter
10 mm
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Length
50 mm
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Carbon Load
18 %
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UNSPSC
41115709
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Application
Oligonucleotide, Cell & Gene Therapy
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Brand
XBridge
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Product Type
Preparative Columns
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Units per Package
1 pk