To help resolve uncertainty at the pace of gene therapy development, XBridge Premier GTx BEH SEC 450 Å, 2.5 µm, 4.6 x 300 mm column provides high resolution and fast size variant separations for AAVs and nucleic acids. AAV monomers and aggregates are ideally resolved using a 450 Å pore size. Unwanted secondary interactions that make it difficult to fully recover your sample and create robust, serotype independent, and stable platform methods are alleviated by hydrophilic MaxPeak High Performance Surface hardware. Industry-leading resolution without undesirable analyte shearing is provided by efficiently packed 2.5 µm particles. Suggested Use: Gel Filtration, Size Exclusion Chromatography, Aggregate, Monomer and Fragment analysis of AAVs and nucleic acids. This column comes equipped with an electronic eConnect column tag containing unique column-specific information. These NFC-enabled device-tagged columns were developed to automatically identify, track and digitally trace column use history. eConnect columns can be used on any HPLC, but its advantages are unlocked when used with the Waters Alliance iS and Alliance iS Bio System running Empower software.
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Chemistry
SEC
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Separation Mode
SEC
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Particle Substrate
Hybrid
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pH Range Min
2.5 pH
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pH Range Max
8 pH
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Temperature Limits
60 C
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Maximum Pressure
4600 psi (317 Bar)
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Endcapped
No
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Bonding Technology
Diol (OH)
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Silanol Activity
Low
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Molecular Weight Range Min
10000
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Molecular Weight Range Max
100000
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Particle Shape
Spherical
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Particle Size
2.5 µm
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Endfitting Type
Parker-style
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Pore Size
450 Å
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Format
Premier Column
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Surface Area
80
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System
UHPLC, UPLC, HPLC
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Particle Technology
BEH
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USP Classification
L33
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Inner Diameter
4.6 mm
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Length
300 mm
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UNSPSC
41115709
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Application
Gene Therapeutics
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Brand
XBridge
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Product Type
Columns
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Units per Package
1 pk
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eConnect
Yes