XL-1 Blue Competent Cells for routine cloning allow blue-white color screening, single-strand rescue of phagemid DNA, and preparation of high-quality plasmid DNA. Derivatives enable higher transformation efficiency, transformation of methylated DNA, choice of antibiotic resistance, and no F episome.For the greatest number of colonies, use electroporation-competent XL1-Blue cells or the high-efficiency derivative, XL2-Blue ultracompetent cells. When ultimate efficiency is not as critical, try the supercompetent-grade, competent-grade, or the subcloning grade competent cells.